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**NAD+ (Nicotinamide Adenine Dinucleotide)** is a vital coenzyme found in every living cell. It plays a crucial role in **cellular metabolism**, **energy production**, **DNA repair**, and **cell signaling**. Here's a breakdown:

 

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### 🔬 **What Is NAD+?**

 

* NAD+ is the **oxidized form** of the molecule (as opposed to NADH, the reduced form).

* It consists of two nucleotides: one with **adenine** and the other with **nicotinamide**.

* It functions primarily as a **coenzyme**, helping enzymes catalyze chemical reactions.

 

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### ⚡️ **Main Functions of NAD+**

 

1. **Energy Production (Metabolism):**

 

   * NAD+ is essential in cellular respiration, especially during the **Krebs cycle** and **electron transport chain**.

   * It carries **electrons** from one reaction to another, which is key to generating **ATP**, the cell’s energy currency.

 

2. **Redox Reactions:**

 

   * NAD+ accepts electrons and becomes NADH, a form that stores energy temporarily.

   * NADH later donates electrons to help produce ATP.

 

3. **DNA Repair:**

 

   * NAD+ is required for the activity of **PARPs (poly ADP-ribose polymerases)**, enzymes that repair damaged DNA.

 

4. **Cell Longevity & Aging:**

 

   * NAD+ activates **sirtuins**, proteins involved in cellular health, stress resistance, and longevity.

   * Declining NAD+ levels are associated with **aging**, **neurodegeneration**, and **metabolic diseases**.

 

5. **Immune & Inflammatory Response:**

 

   * Plays a role in modulating the immune system and inflammatory processes.

 

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### 🧴 **NAD+ Supplementation**

 

* NAD+ levels decline with age, stress, poor diet, and illness.

* Supplement forms include:

 

  * **Nicotinamide riboside (NR)**

  * **Nicotinamide mononucleotide (NMN)**

* **NAD+ IV therapy** is another method to boost systemic levels, often marketed for energy, cognitive function, and recovery.

 

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### 🧠 **Why Is NAD+ Important?**

 

* Vital for:

 

  * Cellular energy

  * Healthy aging

  * Cognitive function

  * Metabolism

  * Muscle and mitochondrial health

 

NAD+

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