**Semaglutide** is a medication primarily used to treat **type 2 diabetes** and **obesity**. It mimics a natural hormone in the body called **GLP-1 (glucagon-like peptide-1)** to regulate blood sugar levels, reduce appetite, and promote weight loss.
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### 🔬 **How Semaglutide Works:**
Semaglutide is a **GLP-1 receptor agonist**. It works by:
* Stimulating insulin release when blood sugar levels are high.
* Reducing the amount of glucose released by the liver.
* Slowing gastric emptying (which helps you feel full longer).
* Acting on the brain to decrease appetite and food intake.
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### 💊 **Uses:**
1. **Type 2 Diabetes:**
* Helps lower blood glucose levels.
* Often prescribed when diet, exercise, and other medications aren't enough.
2. **Obesity & Weight Management:**
* Marketed under different brand names (e.g., **Wegovy**) specifically for chronic weight management in people with or without type 2 diabetes.
* Typically used in conjunction with a reduced-calorie diet and increased physical activity.
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### 🧪 **Formulations & Brand Names:**
* **Ozempic**: Weekly injection for type 2 diabetes.
* **Rybelsus**: Oral tablet for type 2 diabetes.
* **Wegovy**: Higher-dose injection for chronic weight management.
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### ⚠️ **Side Effects:**
Common:
* Nausea
* Vomiting
* Diarrhea
* Constipation
* Loss of appetite
Serious (but rare):
* Pancreatitis
* Gallbladder problems
* Kidney issues
* Risk of thyroid C-cell tumors (in animal studies)
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### ✅ **Benefits:**
* Effective blood sugar control
* Significant weight loss in many patients
* Cardiovascular risk reduction in people with type 2 diabetes and existing heart disease
Sema GLP-1
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